Re: Reproducibility: The risks of the replication drive
I couldn't agree more. See my blog at:http://news.cell.com/cellrepor...
View ArticleRe: Reproducibility: The risks of the replication drive
Thanks for this thoughtful post, Mina. Nature and PLOS, as well as the Reproducibility Initiative, of which I'm co-director, are all worthy efforts.Let me share some preliminary information about the...
View ArticleRe: Reproducibility: The risks of the replication drive
Thank you William, that is a rather amicable description of the Reproducibility Initiative and I salute you for spearheading this. Robustness of effect is a very important issue when trying to take...
View ArticleRe: Reproducibility: The risks of the replication drive
There are reports that not more then 5% of papers failed when tried to replicate. The very fact that we have to take the issue of replication so seriously and spent lots of time (and money) over this...
View ArticleRe: Reproducibility: The risks of the replication drive
I would be a rich man if I had received a penny for every time I heard the expression "in our hands" at a scientific lecture during my (brief) scientific career in biochemistry (back in the 1990's).I...
View ArticleRe: Reproducibility: The risks of the replication drive
Here's a great post about how can try and fix the irreproducibility of scientific papers. We should all strive to "publish every important detail of your method and every control, either in the main...
View ArticleRe: Reproducibility: The risks of the replication drive
Thanks Minna.I appreciate your comments, but do not share your views.First to clarify, in the study in which we reported the Amgen experience, on many occasions we did go back to the original...
View ArticleRe: Reproducibility: The risks of the replication drive
Very interesting. I see this from the perspective of a public health researcher. The problem of reproducibility understandably acquires more complexity with addition of human behaviours (and...
View ArticleRe: Reproducibility: The risks of the replication drive
"A result that is not able to be independently reproduced ... using ... standard laboratory procedures (blinding, controls, validated reagents etc) is not a result. It is simply a 'scientific...
View ArticleRe: Reproducibility: The risks of the replication drive
I am glad to have read Dr. Bissell's piece as well as the responses. I am a humanist who studies research integrity and the responsible conduct of research, and issues of replication clearly fall in...
View ArticleRe: Reproducibility: The risks of the replication drive
I do agree with many of the points about being careful and considerate when replicating published work. But let’s talk about the newcomers a bit more.First of all, I’m not sure I like the word...
View ArticleRe: Reproducibility: The risks of the replication drive
Why would some 'senior' resist replication initiative?The federal investment in R&D is over $140 billion annually. Almost a half of it goes to NIH, NASA, NSF, DOE, and USDA. A huge chunk of it is...
View ArticleRe: Reproducibility: The risks of the replication drive
I think there are a few points that were ignored thus far in the comments:1. In principle it should not be obligatory for an experiment to be reproducible. It is useful to report on surprising results...
View ArticleRe: Reproducibility: The risks of the replication drive
I tried to replicate the LHC experiments and failed. This is a proof that the Higgs boson is not science. Can I have my Nobel please ?
View ArticleRe: Reproducibility: The risks of the replication drive
So replication threatens the cache of irreproducible experiments? For those removed from labs, the more important issue is the robustness and reliability of basic science experiments, not the ability...
View ArticleRe: Reproducibility: The risks of the replication drive
Andrew Gelman, Director of the Applied Statistics Center at Columbia University's response to this is available here: http://andrewgelman.com/2013/1...
View ArticleRe: Reproducibility: The risks of the replication drive
The tone of this commentary and its title both seem to lobby against the growing communal push for replicating basic scientific results. However, Dr. Bissell's own examples pretty clearly support the...
View ArticleRe: Reproducibility: The risks of the replication drive
I couldn't agree more. See my blog at:http://news.cell.com/cellrepor...
View ArticleRe: Reproducibility: The risks of the replication drive
Thanks for this thoughtful post, Mina. Nature and PLOS, as well as the Reproducibility Initiative, of which I'm co-director, are all worthy efforts.Let me share some preliminary information about the...
View ArticleRe: Reproducibility: The risks of the replication drive
Thank you William, that is a rather amicable description of the Reproducibility Initiative and I salute you for spearheading this. Robustness of effect is a very important issue when trying to take...
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